The science of health demands a new standard

With more health products than ever before, it has never been harder to know what information to trust, which products to choose, and what solutions you really need.

Our mission is to change this by creating the most trusted place to discover curated, quality-assessed health & wellness products from around the world.

Scientific rigor is our guiding principle. Before it goes in your body, it goes through us.

How our curation process works

2

Evaluate

Each product then undergoes a comprehensive vetting process over a six-week period. This extensive time window allows us to delve into the details of each standard. Brands are ultimately signed off on by our review committee of leading doctors, scientists, and pharmacologists.

We evaluate products across 11 factors, here are a few of our most important:

2.1 Evaluate

Scientific Rigor

Products should have substantial evidence from peer-reviewed studies. We scrutinize the science to ensure the product is safe and effective. We review how long the supporting science has been around, the strength of the scientific advisory board (SAB) behind it, and the quality of the publishing scientific journal.

This also includes assessing the years of data; the number of supported peer-reviewed articles with large sample sizes and proper randomization (double-blind, placebo-controlled); meta-analyses where present; strong support from scientific experts; and whether studies were done primarily on humans vs animals vs in vitro.

View our levels of evidence
Systematic Reviews & Meta-analysis Randomized Controlled Double Blind Studies Cohort Studies Case Series Case Reports Ideas, Editorials, Opinions Animal Research In Vitro (test tube) Research
2.2 Evaluate

Ingredient Quality

Supplements and wellness products are not regulated by the FDA, so we’ve created our own criteria for what’s considered safe versus not with a NO list to avoid supplements with toxic chemicals, microplastics, preservatives, flavors, colors and other provably harmful ingredients.

500+

Banned ingredients

View list

We do the same for personal care and clean home products and so far have banned 500+ harmful ingredients from parabens, phthalates and oxybenzones – so that you know anything on the Superpower marketplace is a product you can trust.

Finally, we look at independent quality testing for purity, strength, identity, and disintegration from the most reputable sources on the internet including:

View our list of sources

These sources are valuable for evaluating the safety and non-toxicity of products, providing consumers with reliable information to make informed choices.

Environmental Working Group (EWG)
EWG is known for providing tools and resources to make better choices regarding toxic-free, safe products in various categories, including household and consumer products.

The WellBe Non-Toxic Product Database
This database features over 2000 curated non-toxic products vetted by third-party unbiased organizations like Environmental Working Group, Think Dirty, MadeSafe, GreenGuard, ConsumerLab, NSF, and more.

Think Dirty App
This app allows users to check for chemicals in products by entering the product name or scanning the barcode. It provides a toxicity rating and suggests safe and cleaner alternatives.

MadeSafe
This organization provides certification for non-toxic products, ensuring they are free from harmful chemicals.

ConsumerLab
ConsumerLab is known for its comprehensive set of test results, including dosage, phytonutrient levels, and contaminant levels in various products.

Examine
ConsumerLab is known for its comprehensive set of test results, including dosage, phytonutrient levels, and contaminant levels in various products.

NSF Supplement Vitamin Certification
ConsumerLab is known for its comprehensive set of test results, including dosage, phytonutrient levels, and contaminant levels in various products.

Clean Label Project
ConsumerLab is known for its comprehensive set of test results, including dosage, phytonutrient levels, and contaminant levels in various products.

Lab Door
ConsumerLab is known for its comprehensive set of test results, including dosage, phytonutrient levels, and contaminant levels in various products.
2.3 Evaluate

Manufacturing Standards & Sourcing

Manufacturing and sourcing standards are key to understanding product quality.

For supplements, we screen for designations such as CLIA, GMP, NSF, and FDA, which together help inform the quality of the manufacturing and sourcing process.

For food products, our screening extends to examining the quality of the ingredients and methods used in production, such as whether the food is grass-fed, processed vegetable oil free, and organic.

Beyond the products themselves, our holistic evaluation looks across the entire supply chain. We perform company background checks and ensure there are not concerns with products or their supply chains.

2.4 Evaluate

Price & Value

We have a deep commitment to balancing affordability with quality, and price with performance, ensuring that members receive excellent value in every product they order.

We measure product efficacy not just in numbers but also through the satisfaction of the broader customer universe, aiming for brands that have a substantial collection of genuine, positive customer reviews

2.5 Evaluate

Mission Alignment

The brand’s mission must supports or mirrors Superpower’s mission to bring preventative care to all and increase human lifespan and healthspan by preventing chronic disease through the pillars of environment, sleep, mental health, physical health, and nutrition.

3

Monitor

Once a product is accepted into the Superpower marketplace, it's not the end of our due diligence.

We reassess products every six months to ensure continued compliance with our brand standards and the latest research.

Ensuring lifelong quality through regular monitoring and re-evaluation.

As science advances, so will the quality of your lifelong health partnership with Superpower – with product recommendations always reflecting the latest in health innovation and research.

Ultimately, we aim to be so confident with all approved products that our medical team would personally use them themselves or recommend them to their loved ones.

The Members-Only Marketplace Promise

Superpower curates the top 1% of health items from around the world, and our research team conducts comprehensive evaluations to ensure top levels of quality, safety, and scientific robustness.

We ensure that our prices are better than anywhere else on the internet and provide them at a special, negotiated discount to save you money.

We don’t sell our own branded products, we don’t make extra margin on products and our clinical team is NEVER compensated on sales.

Our promise is to always be scientifically rigorous and 100% incentive aligned with you.

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Superpower Marketplace
Superpower Marketplace
Daily Ultimate Essentials Pro: All‑in‑One Supplement - Superpower Marketplace
Daily Ultimate Essentials Pro: All‑in‑One Supplement - Superpower Marketplace
Daily Ultimate Essentials Pro: All‑in‑One Supplement - Superpower Marketplace
Daily Ultimate Essentials Pro: All‑in‑One Supplement - Superpower Marketplace
Daily Ultimate Essentials Pro: All‑in‑One Supplement - Superpower Marketplace
Daily Ultimate Essentials Pro: All‑in‑One Supplement - Superpower Marketplace
Daily Ultimate Essentials Pro: All‑in‑One Supplement - Superpower Marketplace
Daily Ultimate Essentials Pro: All‑in‑One Supplement - Superpower Marketplace
Daily Ultimate Essentials Pro: All‑in‑One Supplement - Superpower Marketplace
Daily Ultimate Essentials Pro: All‑in‑One Supplement - Superpower Marketplace
Daily Ultimate Essentials Pro: All‑in‑One Supplement - Superpower Marketplace
Daily Ultimate Essentials Pro: All‑in‑One Supplement - Superpower Marketplace
Daily Ultimate Essentials Pro: All‑in‑One Supplement - Superpower Marketplace
IM8

Daily Ultimate Essentials Pro: All‑in‑One Supplement

$1999
Daily Ultimate Essentials Pro: All‑in‑One Supplement Variety Pack / 30-Day Supply Subscription (SAVE 32%) ship every 30 days

About Daily Ultimate Essentials Pro: All‑in‑One Supplement

Benefits

IM8 Daily Ultimate Essentials PRO consolidates 90 ingredients into a single 13.6-14.4g daily sachet, designed to replace 16 or more standalone supplements covering cardiovascular, immune, digestive, musculoskeletal, neurological, endocrine, and integumentary systems. The formulation is built around bioavailable ingredient forms across the board - methylated B vitamins, chelated minerals, lichen-derived vegan D3, and all-trans MK-7 K2 - ensuring that dosing on the label translates into actual cellular uptake. A 4-tier gut support system (prebiotic inulin, digestive enzymes, 10 billion CFU spore-based probiotics, and FloraSMART postbiotics) addresses the absorption infrastructure that determines how well any nutrient protocol actually works. The product is NSF Certified for Sport, vegan, allergen-free, gluten-free, non-GMO, and contains no artificial flavors, sweeteners, or added sugar. An active 12-week randomized controlled trial (NCT06655597), sponsored by Prenetics Global and conducted at the San Francisco Research Institute, is currently validating outcomes across energy, digestion, sleep, cognitive performance, and body composition in adults aged 25-60.

  • Closes a common nutritional gaps identified in Superpower member baseline biomarkers - vitamin D, B12, folate, magnesium - using forms the body can actually use
  • Supports mitochondrial energy production via CoQ10 (100 mg clinical dose) and the full active B-vitamin complex
  • Delivers a complete 4-tier gut support system: prebiotic, enzyme, probiotic (10B CFU), and postbiotic in a single sachet
  • Directs calcium to bone and away from arterial walls via a Vitamin D3 (50 mcg) + Vitamin K2 MK-7 (100 mcg) pairing
  • Reduces joint inflammation and supports collagen synthesis with MSM at 1,500 mg - the dose used in clinical trials
  • Supports mood, focus, and serotonin/dopamine modulation via saffron extract (30 mg) and the complete neuro-active B-complex
  • Supports cellular longevity pathways including autophagy (spermidine), antioxidant defense (astaxanthin via AstaPure), and glucose metabolism (berberine HCl) via the CRT8 complex
  • NSF Certified for Sport: independently verified for label accuracy, contaminant absence, and banned substance testing across 280+ substances

Suggested Use

Mix one sachet into 8-12 oz of cold water. Stir or shake well. Take once daily, with or without food.



Available in four SKUs:

  • Acai + Mixed Berries
  • Mango + Passion Fruit
  • Lemon + Orange
  • Variety Pack (assorted flavors)

Sachet weight: 13.6g (Acai + Mixed Berries, Mango + Passion Fruit) to 14.4g (Lemon + Orange), variation due to flavor component composition.

Supporting Research

NCT06655597 - IM8 Daily Ultimate Essentials Pro Randomized Controlled Trial

  • Design: 12-week, randomized, controlled, parallel-group trial
  • Population: 60 adults aged 25-60, BMI 18.5-30, generally healthy
  • Site: San Francisco Research Institute (SFRI)
  • Sponsor: Prenetics Global Ltd.
  • Status: Active, not recruiting
  • Primary endpoint: Body morphology - change in BMI, abdominal circumference, thigh circumference from baseline to week 12
  • Secondary endpoints: Safety and tolerability; subjective energy levels (validated questionnaire); micronutrient blood levels (Vitamin D, B12, folate); digestive symptom scoring; sleep quality; cognitive performance
  • Reported participant outcomes: 95% reported increased energy levels; 85% reported improved digestion and reduced bloating; 80% reported better sleep quality; 75% reported sharper focus and mental clarity
  • Registry: clinicaltrials.gov/study/NCT06655597

This trial evaluates the complete IM8 Daily Ultimate Essentials Pro formulation as consumed - 90 ingredients, full sachet, daily use - which is the only methodologically valid way to assess a multi-ingredient product. Most supplement brands cite ingredient-level studies from unrelated products at different doses; IM8 has funded a controlled trial on its own product.



Note on study status: Results are pending publication. The reported outcome percentages above are from participant-reported measures during the active trial period, not yet peer-reviewed endpoints. The trial remains the strongest available evidence base for this formulation specifically.

How does IM8 Daily Ultimate Essentials Pro benefit my health?

IM8 Daily Ultimate Essentials Pro is designed to function as precision nutritional infrastructure - not general wellness supplementation. For Superpower members, the formulation targets the specific gaps most likely to show up in that data: low or low-normal Vitamin D, insufficient magnesium, suboptimal B12 and folate (particularly in members with MTHFR variants who cannot convert synthetic forms), and oxidative/inflammatory markers that respond to targeted antioxidant load. The bioavailable forms used across the formulation - methylcobalamin, Quatrefolic, P5P, magnesium bisglycinate, all-trans MK-7 - mean the doses on the label correspond to actual cellular delivery.

How is this different from a regular multivitamin?

Three primary differences. First, ingredient forms: most mass-market multivitamins use cheap synthetic forms (cyanocobalamin, folic acid, magnesium oxide) that require hepatic conversion steps many people cannot complete efficiently. IM8 DUE uses the active, converted forms. Second, scope: 90 ingredients spanning 9 organ systems including CoQ10, MSM, adaptogenic mushrooms, spore-based probiotics, postbiotics, saffron, and the CRT8 longevity complex - none of which appear in standard multivitamins. Third, clinical validation: NCT06655597 is a 12-week RCT on the actual product, not borrowed ingredient studies.

Benefits

IM8 Daily Ultimate Essentials PRO consolidates 90 ingredients into a single 13.6-14.4g daily sachet, designed to replace 16 or more standalone supplements covering cardiovascular, immune, digestive, musculoskeletal, neurological, endocrine, and integumentary systems. The formulation is built around bioavailable ingredient forms across the board - methylated B vitamins, chelated minerals, lichen-derived vegan D3, and all-trans MK-7 K2 - ensuring that dosing on the label translates into actual cellular uptake. A 4-tier gut support system (prebiotic inulin, digestive enzymes, 10 billion CFU spore-based probiotics, and FloraSMART postbiotics) addresses the absorption infrastructure that determines how well any nutrient protocol actually works. The product is NSF Certified for Sport, vegan, allergen-free, gluten-free, non-GMO, and contains no artificial flavors, sweeteners, or added sugar. An active 12-week randomized controlled trial (NCT06655597), sponsored by Prenetics Global and conducted at the San Francisco Research Institute, is currently validating outcomes across energy, digestion, sleep, cognitive performance, and body composition in adults aged 25-60.

  • Closes a common nutritional gaps identified in Superpower member baseline biomarkers - vitamin D, B12, folate, magnesium - using forms the body can actually use
  • Supports mitochondrial energy production via CoQ10 (100 mg clinical dose) and the full active B-vitamin complex
  • Delivers a complete 4-tier gut support system: prebiotic, enzyme, probiotic (10B CFU), and postbiotic in a single sachet
  • Directs calcium to bone and away from arterial walls via a Vitamin D3 (50 mcg) + Vitamin K2 MK-7 (100 mcg) pairing
  • Reduces joint inflammation and supports collagen synthesis with MSM at 1,500 mg - the dose used in clinical trials
  • Supports mood, focus, and serotonin/dopamine modulation via saffron extract (30 mg) and the complete neuro-active B-complex
  • Supports cellular longevity pathways including autophagy (spermidine), antioxidant defense (astaxanthin via AstaPure), and glucose metabolism (berberine HCl) via the CRT8 complex
  • NSF Certified for Sport: independently verified for label accuracy, contaminant absence, and banned substance testing across 280+ substances

Suggested Use

Mix one sachet into 8-12 oz of cold water. Stir or shake well. Take once daily, with or without food.



Available in four SKUs:

  • Acai + Mixed Berries
  • Mango + Passion Fruit
  • Lemon + Orange
  • Variety Pack (assorted flavors)

Sachet weight: 13.6g (Acai + Mixed Berries, Mango + Passion Fruit) to 14.4g (Lemon + Orange), variation due to flavor component composition.

Supporting Research

NCT06655597 - IM8 Daily Ultimate Essentials Pro Randomized Controlled Trial

  • Design: 12-week, randomized, controlled, parallel-group trial
  • Population: 60 adults aged 25-60, BMI 18.5-30, generally healthy
  • Site: San Francisco Research Institute (SFRI)
  • Sponsor: Prenetics Global Ltd.
  • Status: Active, not recruiting
  • Primary endpoint: Body morphology - change in BMI, abdominal circumference, thigh circumference from baseline to week 12
  • Secondary endpoints: Safety and tolerability; subjective energy levels (validated questionnaire); micronutrient blood levels (Vitamin D, B12, folate); digestive symptom scoring; sleep quality; cognitive performance
  • Reported participant outcomes: 95% reported increased energy levels; 85% reported improved digestion and reduced bloating; 80% reported better sleep quality; 75% reported sharper focus and mental clarity
  • Registry: clinicaltrials.gov/study/NCT06655597

This trial evaluates the complete IM8 Daily Ultimate Essentials Pro formulation as consumed - 90 ingredients, full sachet, daily use - which is the only methodologically valid way to assess a multi-ingredient product. Most supplement brands cite ingredient-level studies from unrelated products at different doses; IM8 has funded a controlled trial on its own product.



Note on study status: Results are pending publication. The reported outcome percentages above are from participant-reported measures during the active trial period, not yet peer-reviewed endpoints. The trial remains the strongest available evidence base for this formulation specifically.

How does IM8 Daily Ultimate Essentials Pro benefit my health?

IM8 Daily Ultimate Essentials Pro is designed to function as precision nutritional infrastructure - not general wellness supplementation. For Superpower members, the formulation targets the specific gaps most likely to show up in that data: low or low-normal Vitamin D, insufficient magnesium, suboptimal B12 and folate (particularly in members with MTHFR variants who cannot convert synthetic forms), and oxidative/inflammatory markers that respond to targeted antioxidant load. The bioavailable forms used across the formulation - methylcobalamin, Quatrefolic, P5P, magnesium bisglycinate, all-trans MK-7 - mean the doses on the label correspond to actual cellular delivery.

How is this different from a regular multivitamin?

Three primary differences. First, ingredient forms: most mass-market multivitamins use cheap synthetic forms (cyanocobalamin, folic acid, magnesium oxide) that require hepatic conversion steps many people cannot complete efficiently. IM8 DUE uses the active, converted forms. Second, scope: 90 ingredients spanning 9 organ systems including CoQ10, MSM, adaptogenic mushrooms, spore-based probiotics, postbiotics, saffron, and the CRT8 longevity complex - none of which appear in standard multivitamins. Third, clinical validation: NCT06655597 is a 12-week RCT on the actual product, not borrowed ingredient studies.

Benefits

IM8 Daily Ultimate Essentials PRO consolidates 90 ingredients into a single 13.6-14.4g daily sachet, designed to replace 16 or more standalone supplements covering cardiovascular, immune, digestive, musculoskeletal, neurological, endocrine, and integumentary systems. The formulation is built around bioavailable ingredient forms across the board - methylated B vitamins, chelated minerals, lichen-derived vegan D3, and all-trans MK-7 K2 - ensuring that dosing on the label translates into actual cellular uptake. A 4-tier gut support system (prebiotic inulin, digestive enzymes, 10 billion CFU spore-based probiotics, and FloraSMART postbiotics) addresses the absorption infrastructure that determines how well any nutrient protocol actually works. The product is NSF Certified for Sport, vegan, allergen-free, gluten-free, non-GMO, and contains no artificial flavors, sweeteners, or added sugar. An active 12-week randomized controlled trial (NCT06655597), sponsored by Prenetics Global and conducted at the San Francisco Research Institute, is currently validating outcomes across energy, digestion, sleep, cognitive performance, and body composition in adults aged 25-60.

  • Closes a common nutritional gaps identified in Superpower member baseline biomarkers - vitamin D, B12, folate, magnesium - using forms the body can actually use
  • Supports mitochondrial energy production via CoQ10 (100 mg clinical dose) and the full active B-vitamin complex
  • Delivers a complete 4-tier gut support system: prebiotic, enzyme, probiotic (10B CFU), and postbiotic in a single sachet
  • Directs calcium to bone and away from arterial walls via a Vitamin D3 (50 mcg) + Vitamin K2 MK-7 (100 mcg) pairing
  • Reduces joint inflammation and supports collagen synthesis with MSM at 1,500 mg - the dose used in clinical trials
  • Supports mood, focus, and serotonin/dopamine modulation via saffron extract (30 mg) and the complete neuro-active B-complex
  • Supports cellular longevity pathways including autophagy (spermidine), antioxidant defense (astaxanthin via AstaPure), and glucose metabolism (berberine HCl) via the CRT8 complex
  • NSF Certified for Sport: independently verified for label accuracy, contaminant absence, and banned substance testing across 280+ substances

Suggested Use

Mix one sachet into 8-12 oz of cold water. Stir or shake well. Take once daily, with or without food.



Available in four SKUs:

  • Acai + Mixed Berries
  • Mango + Passion Fruit
  • Lemon + Orange
  • Variety Pack (assorted flavors)

Sachet weight: 13.6g (Acai + Mixed Berries, Mango + Passion Fruit) to 14.4g (Lemon + Orange), variation due to flavor component composition.

Supporting Research

NCT06655597 - IM8 Daily Ultimate Essentials Pro Randomized Controlled Trial

  • Design: 12-week, randomized, controlled, parallel-group trial
  • Population: 60 adults aged 25-60, BMI 18.5-30, generally healthy
  • Site: San Francisco Research Institute (SFRI)
  • Sponsor: Prenetics Global Ltd.
  • Status: Active, not recruiting
  • Primary endpoint: Body morphology - change in BMI, abdominal circumference, thigh circumference from baseline to week 12
  • Secondary endpoints: Safety and tolerability; subjective energy levels (validated questionnaire); micronutrient blood levels (Vitamin D, B12, folate); digestive symptom scoring; sleep quality; cognitive performance
  • Reported participant outcomes: 95% reported increased energy levels; 85% reported improved digestion and reduced bloating; 80% reported better sleep quality; 75% reported sharper focus and mental clarity
  • Registry: clinicaltrials.gov/study/NCT06655597

This trial evaluates the complete IM8 Daily Ultimate Essentials Pro formulation as consumed - 90 ingredients, full sachet, daily use - which is the only methodologically valid way to assess a multi-ingredient product. Most supplement brands cite ingredient-level studies from unrelated products at different doses; IM8 has funded a controlled trial on its own product.



Note on study status: Results are pending publication. The reported outcome percentages above are from participant-reported measures during the active trial period, not yet peer-reviewed endpoints. The trial remains the strongest available evidence base for this formulation specifically.

How does IM8 Daily Ultimate Essentials Pro benefit my health?

IM8 Daily Ultimate Essentials Pro is designed to function as precision nutritional infrastructure - not general wellness supplementation. For Superpower members, the formulation targets the specific gaps most likely to show up in that data: low or low-normal Vitamin D, insufficient magnesium, suboptimal B12 and folate (particularly in members with MTHFR variants who cannot convert synthetic forms), and oxidative/inflammatory markers that respond to targeted antioxidant load. The bioavailable forms used across the formulation - methylcobalamin, Quatrefolic, P5P, magnesium bisglycinate, all-trans MK-7 - mean the doses on the label correspond to actual cellular delivery.

How is this different from a regular multivitamin?

Three primary differences. First, ingredient forms: most mass-market multivitamins use cheap synthetic forms (cyanocobalamin, folic acid, magnesium oxide) that require hepatic conversion steps many people cannot complete efficiently. IM8 DUE uses the active, converted forms. Second, scope: 90 ingredients spanning 9 organ systems including CoQ10, MSM, adaptogenic mushrooms, spore-based probiotics, postbiotics, saffron, and the CRT8 longevity complex - none of which appear in standard multivitamins. Third, clinical validation: NCT06655597 is a 12-week RCT on the actual product, not borrowed ingredient studies.

Benefits

IM8 Daily Ultimate Essentials PRO consolidates 90 ingredients into a single 13.6-14.4g daily sachet, designed to replace 16 or more standalone supplements covering cardiovascular, immune, digestive, musculoskeletal, neurological, endocrine, and integumentary systems. The formulation is built around bioavailable ingredient forms across the board - methylated B vitamins, chelated minerals, lichen-derived vegan D3, and all-trans MK-7 K2 - ensuring that dosing on the label translates into actual cellular uptake. A 4-tier gut support system (prebiotic inulin, digestive enzymes, 10 billion CFU spore-based probiotics, and FloraSMART postbiotics) addresses the absorption infrastructure that determines how well any nutrient protocol actually works. The product is NSF Certified for Sport, vegan, allergen-free, gluten-free, non-GMO, and contains no artificial flavors, sweeteners, or added sugar. An active 12-week randomized controlled trial (NCT06655597), sponsored by Prenetics Global and conducted at the San Francisco Research Institute, is currently validating outcomes across energy, digestion, sleep, cognitive performance, and body composition in adults aged 25-60.

  • Closes a common nutritional gaps identified in Superpower member baseline biomarkers - vitamin D, B12, folate, magnesium - using forms the body can actually use
  • Supports mitochondrial energy production via CoQ10 (100 mg clinical dose) and the full active B-vitamin complex
  • Delivers a complete 4-tier gut support system: prebiotic, enzyme, probiotic (10B CFU), and postbiotic in a single sachet
  • Directs calcium to bone and away from arterial walls via a Vitamin D3 (50 mcg) + Vitamin K2 MK-7 (100 mcg) pairing
  • Reduces joint inflammation and supports collagen synthesis with MSM at 1,500 mg - the dose used in clinical trials
  • Supports mood, focus, and serotonin/dopamine modulation via saffron extract (30 mg) and the complete neuro-active B-complex
  • Supports cellular longevity pathways including autophagy (spermidine), antioxidant defense (astaxanthin via AstaPure), and glucose metabolism (berberine HCl) via the CRT8 complex
  • NSF Certified for Sport: independently verified for label accuracy, contaminant absence, and banned substance testing across 280+ substances

Suggested Use

Mix one sachet into 8-12 oz of cold water. Stir or shake well. Take once daily, with or without food.



Available in four SKUs:

  • Acai + Mixed Berries
  • Mango + Passion Fruit
  • Lemon + Orange
  • Variety Pack (assorted flavors)

Sachet weight: 13.6g (Acai + Mixed Berries, Mango + Passion Fruit) to 14.4g (Lemon + Orange), variation due to flavor component composition.

Supporting Research

NCT06655597 - IM8 Daily Ultimate Essentials Pro Randomized Controlled Trial

  • Design: 12-week, randomized, controlled, parallel-group trial
  • Population: 60 adults aged 25-60, BMI 18.5-30, generally healthy
  • Site: San Francisco Research Institute (SFRI)
  • Sponsor: Prenetics Global Ltd.
  • Status: Active, not recruiting
  • Primary endpoint: Body morphology - change in BMI, abdominal circumference, thigh circumference from baseline to week 12
  • Secondary endpoints: Safety and tolerability; subjective energy levels (validated questionnaire); micronutrient blood levels (Vitamin D, B12, folate); digestive symptom scoring; sleep quality; cognitive performance
  • Reported participant outcomes: 95% reported increased energy levels; 85% reported improved digestion and reduced bloating; 80% reported better sleep quality; 75% reported sharper focus and mental clarity
  • Registry: clinicaltrials.gov/study/NCT06655597

This trial evaluates the complete IM8 Daily Ultimate Essentials Pro formulation as consumed - 90 ingredients, full sachet, daily use - which is the only methodologically valid way to assess a multi-ingredient product. Most supplement brands cite ingredient-level studies from unrelated products at different doses; IM8 has funded a controlled trial on its own product.



Note on study status: Results are pending publication. The reported outcome percentages above are from participant-reported measures during the active trial period, not yet peer-reviewed endpoints. The trial remains the strongest available evidence base for this formulation specifically.

How does IM8 Daily Ultimate Essentials Pro benefit my health?

IM8 Daily Ultimate Essentials Pro is designed to function as precision nutritional infrastructure - not general wellness supplementation. For Superpower members, the formulation targets the specific gaps most likely to show up in that data: low or low-normal Vitamin D, insufficient magnesium, suboptimal B12 and folate (particularly in members with MTHFR variants who cannot convert synthetic forms), and oxidative/inflammatory markers that respond to targeted antioxidant load. The bioavailable forms used across the formulation - methylcobalamin, Quatrefolic, P5P, magnesium bisglycinate, all-trans MK-7 - mean the doses on the label correspond to actual cellular delivery.

How is this different from a regular multivitamin?

Three primary differences. First, ingredient forms: most mass-market multivitamins use cheap synthetic forms (cyanocobalamin, folic acid, magnesium oxide) that require hepatic conversion steps many people cannot complete efficiently. IM8 DUE uses the active, converted forms. Second, scope: 90 ingredients spanning 9 organ systems including CoQ10, MSM, adaptogenic mushrooms, spore-based probiotics, postbiotics, saffron, and the CRT8 longevity complex - none of which appear in standard multivitamins. Third, clinical validation: NCT06655597 is a 12-week RCT on the actual product, not borrowed ingredient studies.

Benefits

IM8 Daily Ultimate Essentials PRO consolidates 90 ingredients into a single 13.6-14.4g daily sachet, designed to replace 16 or more standalone supplements covering cardiovascular, immune, digestive, musculoskeletal, neurological, endocrine, and integumentary systems. The formulation is built around bioavailable ingredient forms across the board - methylated B vitamins, chelated minerals, lichen-derived vegan D3, and all-trans MK-7 K2 - ensuring that dosing on the label translates into actual cellular uptake. A 4-tier gut support system (prebiotic inulin, digestive enzymes, 10 billion CFU spore-based probiotics, and FloraSMART postbiotics) addresses the absorption infrastructure that determines how well any nutrient protocol actually works. The product is NSF Certified for Sport, vegan, allergen-free, gluten-free, non-GMO, and contains no artificial flavors, sweeteners, or added sugar. An active 12-week randomized controlled trial (NCT06655597), sponsored by Prenetics Global and conducted at the San Francisco Research Institute, is currently validating outcomes across energy, digestion, sleep, cognitive performance, and body composition in adults aged 25-60.

  • Closes a common nutritional gaps identified in Superpower member baseline biomarkers - vitamin D, B12, folate, magnesium - using forms the body can actually use
  • Supports mitochondrial energy production via CoQ10 (100 mg clinical dose) and the full active B-vitamin complex
  • Delivers a complete 4-tier gut support system: prebiotic, enzyme, probiotic (10B CFU), and postbiotic in a single sachet
  • Directs calcium to bone and away from arterial walls via a Vitamin D3 (50 mcg) + Vitamin K2 MK-7 (100 mcg) pairing
  • Reduces joint inflammation and supports collagen synthesis with MSM at 1,500 mg - the dose used in clinical trials
  • Supports mood, focus, and serotonin/dopamine modulation via saffron extract (30 mg) and the complete neuro-active B-complex
  • Supports cellular longevity pathways including autophagy (spermidine), antioxidant defense (astaxanthin via AstaPure), and glucose metabolism (berberine HCl) via the CRT8 complex
  • NSF Certified for Sport: independently verified for label accuracy, contaminant absence, and banned substance testing across 280+ substances

Suggested Use

Mix one sachet into 8-12 oz of cold water. Stir or shake well. Take once daily, with or without food.



Available in four SKUs:

  • Acai + Mixed Berries
  • Mango + Passion Fruit
  • Lemon + Orange
  • Variety Pack (assorted flavors)

Sachet weight: 13.6g (Acai + Mixed Berries, Mango + Passion Fruit) to 14.4g (Lemon + Orange), variation due to flavor component composition.

Supporting Research

NCT06655597 - IM8 Daily Ultimate Essentials Pro Randomized Controlled Trial

  • Design: 12-week, randomized, controlled, parallel-group trial
  • Population: 60 adults aged 25-60, BMI 18.5-30, generally healthy
  • Site: San Francisco Research Institute (SFRI)
  • Sponsor: Prenetics Global Ltd.
  • Status: Active, not recruiting
  • Primary endpoint: Body morphology - change in BMI, abdominal circumference, thigh circumference from baseline to week 12
  • Secondary endpoints: Safety and tolerability; subjective energy levels (validated questionnaire); micronutrient blood levels (Vitamin D, B12, folate); digestive symptom scoring; sleep quality; cognitive performance
  • Reported participant outcomes: 95% reported increased energy levels; 85% reported improved digestion and reduced bloating; 80% reported better sleep quality; 75% reported sharper focus and mental clarity
  • Registry: clinicaltrials.gov/study/NCT06655597

This trial evaluates the complete IM8 Daily Ultimate Essentials Pro formulation as consumed - 90 ingredients, full sachet, daily use - which is the only methodologically valid way to assess a multi-ingredient product. Most supplement brands cite ingredient-level studies from unrelated products at different doses; IM8 has funded a controlled trial on its own product.



Note on study status: Results are pending publication. The reported outcome percentages above are from participant-reported measures during the active trial period, not yet peer-reviewed endpoints. The trial remains the strongest available evidence base for this formulation specifically.

How does IM8 Daily Ultimate Essentials Pro benefit my health?

IM8 Daily Ultimate Essentials Pro is designed to function as precision nutritional infrastructure - not general wellness supplementation. For Superpower members, the formulation targets the specific gaps most likely to show up in that data: low or low-normal Vitamin D, insufficient magnesium, suboptimal B12 and folate (particularly in members with MTHFR variants who cannot convert synthetic forms), and oxidative/inflammatory markers that respond to targeted antioxidant load. The bioavailable forms used across the formulation - methylcobalamin, Quatrefolic, P5P, magnesium bisglycinate, all-trans MK-7 - mean the doses on the label correspond to actual cellular delivery.

How is this different from a regular multivitamin?

Three primary differences. First, ingredient forms: most mass-market multivitamins use cheap synthetic forms (cyanocobalamin, folic acid, magnesium oxide) that require hepatic conversion steps many people cannot complete efficiently. IM8 DUE uses the active, converted forms. Second, scope: 90 ingredients spanning 9 organ systems including CoQ10, MSM, adaptogenic mushrooms, spore-based probiotics, postbiotics, saffron, and the CRT8 longevity complex - none of which appear in standard multivitamins. Third, clinical validation: NCT06655597 is a 12-week RCT on the actual product, not borrowed ingredient studies.

For Superpower Members, text your private concierge at any time with any question

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The Superpower Research Team curates the top 1% of health items from around the world for top levels of ingredient quality, safety, and scientific efficacy.

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