The science of health demands a new standard

With more health products than ever before, it has never been harder to know what information to trust, which products to choose, and what solutions you really need.

Our mission is to change this by creating the most trusted place to discover curated, quality-assessed health & wellness products from around the world.

Scientific rigor is our guiding principle. Before it goes in your body, it goes through us.

How our curation process works

2

Evaluate

Each product then undergoes a comprehensive vetting process over a six-week period. This extensive time window allows us to delve into the details of each standard. Brands are ultimately signed off on by our review committee of leading doctors, scientists, and pharmacologists.

We evaluate products across 11 factors, here are a few of our most important:

2.1 Evaluate

Scientific Rigor

Products should have substantial evidence from peer-reviewed studies. We scrutinize the science to ensure the product is safe and effective. We review how long the supporting science has been around, the strength of the scientific advisory board (SAB) behind it, and the quality of the publishing scientific journal.

This also includes assessing the years of data; the number of supported peer-reviewed articles with large sample sizes and proper randomization (double-blind, placebo-controlled); meta-analyses where present; strong support from scientific experts; and whether studies were done primarily on humans vs animals vs in vitro.

View our levels of evidence
Systematic Reviews & Meta-analysis Randomized Controlled Double Blind Studies Cohort Studies Case Series Case Reports Ideas, Editorials, Opinions Animal Research In Vitro (test tube) Research
2.2 Evaluate

Ingredient Quality

Supplements and wellness products are not regulated by the FDA, so we’ve created our own criteria for what’s considered safe versus not with a NO list to avoid supplements with toxic chemicals, microplastics, preservatives, flavors, colors and other provably harmful ingredients.

500+

Banned ingredients

View list

We do the same for personal care and clean home products and so far have banned 500+ harmful ingredients from parabens, phthalates and oxybenzones – so that you know anything on the Superpower marketplace is a product you can trust.

Finally, we look at independent quality testing for purity, strength, identity, and disintegration from the most reputable sources on the internet including:

View our list of sources

These sources are valuable for evaluating the safety and non-toxicity of products, providing consumers with reliable information to make informed choices.

Environmental Working Group (EWG)
EWG is known for providing tools and resources to make better choices regarding toxic-free, safe products in various categories, including household and consumer products.

The WellBe Non-Toxic Product Database
This database features over 2000 curated non-toxic products vetted by third-party unbiased organizations like Environmental Working Group, Think Dirty, MadeSafe, GreenGuard, ConsumerLab, NSF, and more.

Think Dirty App
This app allows users to check for chemicals in products by entering the product name or scanning the barcode. It provides a toxicity rating and suggests safe and cleaner alternatives.

MadeSafe
This organization provides certification for non-toxic products, ensuring they are free from harmful chemicals.

ConsumerLab
ConsumerLab is known for its comprehensive set of test results, including dosage, phytonutrient levels, and contaminant levels in various products.

Examine
ConsumerLab is known for its comprehensive set of test results, including dosage, phytonutrient levels, and contaminant levels in various products.

NSF Supplement Vitamin Certification
ConsumerLab is known for its comprehensive set of test results, including dosage, phytonutrient levels, and contaminant levels in various products.

Clean Label Project
ConsumerLab is known for its comprehensive set of test results, including dosage, phytonutrient levels, and contaminant levels in various products.

Lab Door
ConsumerLab is known for its comprehensive set of test results, including dosage, phytonutrient levels, and contaminant levels in various products.
2.3 Evaluate

Manufacturing Standards & Sourcing

Manufacturing and sourcing standards are key to understanding product quality.

For supplements, we screen for designations such as CLIA, GMP, NSF, and FDA, which together help inform the quality of the manufacturing and sourcing process.

For food products, our screening extends to examining the quality of the ingredients and methods used in production, such as whether the food is grass-fed, processed vegetable oil free, and organic.

Beyond the products themselves, our holistic evaluation looks across the entire supply chain. We perform company background checks and ensure there are not concerns with products or their supply chains.

2.4 Evaluate

Price & Value

We have a deep commitment to balancing affordability with quality, and price with performance, ensuring that members receive excellent value in every product they order.

We measure product efficacy not just in numbers but also through the satisfaction of the broader customer universe, aiming for brands that have a substantial collection of genuine, positive customer reviews

2.5 Evaluate

Mission Alignment

The brand’s mission must supports or mirrors Superpower’s mission to bring preventative care to all and increase human lifespan and healthspan by preventing chronic disease through the pillars of environment, sleep, mental health, physical health, and nutrition.

3

Monitor

Once a product is accepted into the Superpower marketplace, it's not the end of our due diligence.

We reassess products every six months to ensure continued compliance with our brand standards and the latest research.

Ensuring lifelong quality through regular monitoring and re-evaluation.

As science advances, so will the quality of your lifelong health partnership with Superpower – with product recommendations always reflecting the latest in health innovation and research.

Ultimately, we aim to be so confident with all approved products that our medical team would personally use them themselves or recommend them to their loved ones.

The Members-Only Marketplace Promise

Superpower curates the top 1% of health items from around the world, and our research team conducts comprehensive evaluations to ensure top levels of quality, safety, and scientific robustness.

We ensure that our prices are better than anywhere else on the internet and provide them at a special, negotiated discount to save you money.

We don’t sell our own branded products, we don’t make extra margin on products and our clinical team is NEVER compensated on sales.

Our promise is to always be scientifically rigorous and 100% incentive aligned with you.

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Superpower Marketplace
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Tadalafil
RX

Tadalafil

Elevate intimacy with Tadalafil's powerful blood flow enhancement for heightened performance and satisfaction.

Personalized Prescription

Free Priority Shipping

Ongoing Care & Support
Tadalafil
Tadalafil Default Title

The science of Tadalafil

Active ingredients

Tadalafil, the active ingredient in Tadalafil medications, is a phosphodiesterase type 5 (PDE5) inhibitor. Inactive ingredients in Tadalafil tablets may include lactose monohydrate, hydroxypropyl cellulose, croscarmellose sodium, magnesium stearate, hypromellose, iron oxide, titanium dioxide, and triacetin.

Mechanism

Tadalafil, a phosphodiesterase type 5 (PDE5) inhibitor, works by enhancing the effects of nitric oxide, a chemical that relaxes smooth muscles in the blood vessels. This relaxation increases blood flow to specific areas of the body, primarily assisting in the treatment of erectile dysfunction.

History

Tadalafil, introduced in 2003, is a phosphodiesterase type 5 (PDE5) inhibitor used to treat erectile dysfunction (ED). Originally developed by Eli Lilly and Company, Tadalafil has gained widespread use as an effective and long-lasting option for ED, with its approval extended to the treatment of benign prostatic hyperplasia and pulmonary arterial hypertension.

How to get Tadalafil

Get started

Frequently Asked Questions

Am I a good candidate?

A good candidate for Tadalafil typically includes individuals experiencing erectile dysfunction or symptoms of benign prostatic hyperplasia, after consulting with a healthcare provider to assess their medical history and overall health. Compatibility with other medications, cardiovascular health, and lifestyle factors are also important considerations in determining suitability for Tadalafil usage.

What states is this available in?

California, New York, Florida, Texas, Colorado and Nevada

Supporting science and sources

How do I use Tadalafil?

Tadalafil is typically taken orally before anticipated sexual activity, with or without food, as directed by a healthcare professional.

How does Tadalafil effect my body?

Tadalafil, upon oral administration, is rapidly absorbed in the gastrointestinal tract, with peak plasma concentrations reached within 2 hours. It undergoes hepatic metabolism primarily by the cytochrome P450 enzyme system, particularly CYP3A4. The major metabolite is further excreted in the feces and urine.

Special Considerations

Tadalafil is contraindicated in individuals with a known hypersensitivity to the drug or any of its components. It is essential to exercise caution in patients with cardiovascular conditions, as the use of Tadalafil may pose risks, particularly during sexual activity. Individuals with a history of priapism or conditions predisposing to priapism, such as sickle cell anemia, should use Tadalafil cautiously. Before using Tadalafil, consultation with healthcare professionals is recommended, especially for individuals with severe hepatic or renal impairment. As with any medication, it is crucial to follow prescribed dosages and seek immediate medical attention in case of adverse reactions.

How do I safely store Tadalafil?

Tadalafil should be stored at room temperature away from moisture, heat, and light. Keeping the medication in its original packaging and away from children and pets is essential to maintain its stability and effectiveness.

What’s the difference between Tadalafil and Cialis?

Tadalafil is the active ingredient used in Cialis and is the generic equivalent. As clinically evidenced, Tadalafil is just as safe and effective as branded Cialis; it works for the same amount of time and delivers the same lasting effects.

What are the advantages of Tadalafil over other ED meds?

Unlike other ED medications, Tadalafil can be taken daily. This means you can be intimate at any time, rather than needing to take a pill from time to time, as needed, like other brands.



Clinical evidence also supports Tadalafil for a variety of health and longevity benefits due to its ability to act as an anti-inflammatory, improve cognitive function, and improve blood flow to major organs.

Can Tadalafil be used for purposes other than erectile dysfunction?

Yes, besides treating erectile dysfunction, Tadalafil is also prescribed for managing symptoms of benign prostatic hyperplasia (BPH), a condition characterized by an enlarged prostate gland. By relaxing the muscles in the prostate and bladder, Tadalafil can help improve urinary symptoms associated with BPH, such as difficulty urinating or frequent urination.

What does off-label usage mean?

Off-label usage refers to the practice of prescribing or using a medication, medical device, or treatment for a purpose that is not approved by regulatory authorities, such as the FDA (Food and Drug Administration) in the United States. This means that the medication is being used in a manner or for a condition that is not specifically listed on its label or approved product information. Off-label usage may occur when healthcare professionals believe that the treatment may be beneficial for a particular condition, based on clinical judgment, research, or anecdotal evidence, even if it has not been formally approved for that specific use.

Am I a good candidate?

A good candidate for Tadalafil typically includes individuals experiencing erectile dysfunction or symptoms of benign prostatic hyperplasia, after consulting with a healthcare provider to assess their medical history and overall health. Compatibility with other medications, cardiovascular health, and lifestyle factors are also important considerations in determining suitability for Tadalafil usage.

What states is this available in?

California, New York, Florida, Texas, Colorado and Nevada

Supporting science and sources

How do I use Tadalafil?

Tadalafil is typically taken orally before anticipated sexual activity, with or without food, as directed by a healthcare professional.

How does Tadalafil effect my body?

Tadalafil, upon oral administration, is rapidly absorbed in the gastrointestinal tract, with peak plasma concentrations reached within 2 hours. It undergoes hepatic metabolism primarily by the cytochrome P450 enzyme system, particularly CYP3A4. The major metabolite is further excreted in the feces and urine.

Special Considerations

Tadalafil is contraindicated in individuals with a known hypersensitivity to the drug or any of its components. It is essential to exercise caution in patients with cardiovascular conditions, as the use of Tadalafil may pose risks, particularly during sexual activity. Individuals with a history of priapism or conditions predisposing to priapism, such as sickle cell anemia, should use Tadalafil cautiously. Before using Tadalafil, consultation with healthcare professionals is recommended, especially for individuals with severe hepatic or renal impairment. As with any medication, it is crucial to follow prescribed dosages and seek immediate medical attention in case of adverse reactions.

How do I safely store Tadalafil?

Tadalafil should be stored at room temperature away from moisture, heat, and light. Keeping the medication in its original packaging and away from children and pets is essential to maintain its stability and effectiveness.

What’s the difference between Tadalafil and Cialis?

Tadalafil is the active ingredient used in Cialis and is the generic equivalent. As clinically evidenced, Tadalafil is just as safe and effective as branded Cialis; it works for the same amount of time and delivers the same lasting effects.

What are the advantages of Tadalafil over other ED meds?

Unlike other ED medications, Tadalafil can be taken daily. This means you can be intimate at any time, rather than needing to take a pill from time to time, as needed, like other brands.



Clinical evidence also supports Tadalafil for a variety of health and longevity benefits due to its ability to act as an anti-inflammatory, improve cognitive function, and improve blood flow to major organs.

Can Tadalafil be used for purposes other than erectile dysfunction?

Yes, besides treating erectile dysfunction, Tadalafil is also prescribed for managing symptoms of benign prostatic hyperplasia (BPH), a condition characterized by an enlarged prostate gland. By relaxing the muscles in the prostate and bladder, Tadalafil can help improve urinary symptoms associated with BPH, such as difficulty urinating or frequent urination.

What does off-label usage mean?

Off-label usage refers to the practice of prescribing or using a medication, medical device, or treatment for a purpose that is not approved by regulatory authorities, such as the FDA (Food and Drug Administration) in the United States. This means that the medication is being used in a manner or for a condition that is not specifically listed on its label or approved product information. Off-label usage may occur when healthcare professionals believe that the treatment may be beneficial for a particular condition, based on clinical judgment, research, or anecdotal evidence, even if it has not been formally approved for that specific use.

Am I a good candidate?

A good candidate for Tadalafil typically includes individuals experiencing erectile dysfunction or symptoms of benign prostatic hyperplasia, after consulting with a healthcare provider to assess their medical history and overall health. Compatibility with other medications, cardiovascular health, and lifestyle factors are also important considerations in determining suitability for Tadalafil usage.

What states is this available in?

California, New York, Florida, Texas, Colorado and Nevada

Supporting science and sources

How do I use Tadalafil?

Tadalafil is typically taken orally before anticipated sexual activity, with or without food, as directed by a healthcare professional.

How does Tadalafil effect my body?

Tadalafil, upon oral administration, is rapidly absorbed in the gastrointestinal tract, with peak plasma concentrations reached within 2 hours. It undergoes hepatic metabolism primarily by the cytochrome P450 enzyme system, particularly CYP3A4. The major metabolite is further excreted in the feces and urine.

Special Considerations

Tadalafil is contraindicated in individuals with a known hypersensitivity to the drug or any of its components. It is essential to exercise caution in patients with cardiovascular conditions, as the use of Tadalafil may pose risks, particularly during sexual activity. Individuals with a history of priapism or conditions predisposing to priapism, such as sickle cell anemia, should use Tadalafil cautiously. Before using Tadalafil, consultation with healthcare professionals is recommended, especially for individuals with severe hepatic or renal impairment. As with any medication, it is crucial to follow prescribed dosages and seek immediate medical attention in case of adverse reactions.

How do I safely store Tadalafil?

Tadalafil should be stored at room temperature away from moisture, heat, and light. Keeping the medication in its original packaging and away from children and pets is essential to maintain its stability and effectiveness.

What’s the difference between Tadalafil and Cialis?

Tadalafil is the active ingredient used in Cialis and is the generic equivalent. As clinically evidenced, Tadalafil is just as safe and effective as branded Cialis; it works for the same amount of time and delivers the same lasting effects.

What are the advantages of Tadalafil over other ED meds?

Unlike other ED medications, Tadalafil can be taken daily. This means you can be intimate at any time, rather than needing to take a pill from time to time, as needed, like other brands.



Clinical evidence also supports Tadalafil for a variety of health and longevity benefits due to its ability to act as an anti-inflammatory, improve cognitive function, and improve blood flow to major organs.

Can Tadalafil be used for purposes other than erectile dysfunction?

Yes, besides treating erectile dysfunction, Tadalafil is also prescribed for managing symptoms of benign prostatic hyperplasia (BPH), a condition characterized by an enlarged prostate gland. By relaxing the muscles in the prostate and bladder, Tadalafil can help improve urinary symptoms associated with BPH, such as difficulty urinating or frequent urination.

What does off-label usage mean?

Off-label usage refers to the practice of prescribing or using a medication, medical device, or treatment for a purpose that is not approved by regulatory authorities, such as the FDA (Food and Drug Administration) in the United States. This means that the medication is being used in a manner or for a condition that is not specifically listed on its label or approved product information. Off-label usage may occur when healthcare professionals believe that the treatment may be beneficial for a particular condition, based on clinical judgment, research, or anecdotal evidence, even if it has not been formally approved for that specific use.

Am I a good candidate?

A good candidate for Tadalafil typically includes individuals experiencing erectile dysfunction or symptoms of benign prostatic hyperplasia, after consulting with a healthcare provider to assess their medical history and overall health. Compatibility with other medications, cardiovascular health, and lifestyle factors are also important considerations in determining suitability for Tadalafil usage.

What states is this available in?

California, New York, Florida, Texas, Colorado and Nevada

Supporting science and sources

How do I use Tadalafil?

Tadalafil is typically taken orally before anticipated sexual activity, with or without food, as directed by a healthcare professional.

How does Tadalafil effect my body?

Tadalafil, upon oral administration, is rapidly absorbed in the gastrointestinal tract, with peak plasma concentrations reached within 2 hours. It undergoes hepatic metabolism primarily by the cytochrome P450 enzyme system, particularly CYP3A4. The major metabolite is further excreted in the feces and urine.

Special Considerations

Tadalafil is contraindicated in individuals with a known hypersensitivity to the drug or any of its components. It is essential to exercise caution in patients with cardiovascular conditions, as the use of Tadalafil may pose risks, particularly during sexual activity. Individuals with a history of priapism or conditions predisposing to priapism, such as sickle cell anemia, should use Tadalafil cautiously. Before using Tadalafil, consultation with healthcare professionals is recommended, especially for individuals with severe hepatic or renal impairment. As with any medication, it is crucial to follow prescribed dosages and seek immediate medical attention in case of adverse reactions.

How do I safely store Tadalafil?

Tadalafil should be stored at room temperature away from moisture, heat, and light. Keeping the medication in its original packaging and away from children and pets is essential to maintain its stability and effectiveness.

What’s the difference between Tadalafil and Cialis?

Tadalafil is the active ingredient used in Cialis and is the generic equivalent. As clinically evidenced, Tadalafil is just as safe and effective as branded Cialis; it works for the same amount of time and delivers the same lasting effects.

What are the advantages of Tadalafil over other ED meds?

Unlike other ED medications, Tadalafil can be taken daily. This means you can be intimate at any time, rather than needing to take a pill from time to time, as needed, like other brands.



Clinical evidence also supports Tadalafil for a variety of health and longevity benefits due to its ability to act as an anti-inflammatory, improve cognitive function, and improve blood flow to major organs.

Can Tadalafil be used for purposes other than erectile dysfunction?

Yes, besides treating erectile dysfunction, Tadalafil is also prescribed for managing symptoms of benign prostatic hyperplasia (BPH), a condition characterized by an enlarged prostate gland. By relaxing the muscles in the prostate and bladder, Tadalafil can help improve urinary symptoms associated with BPH, such as difficulty urinating or frequent urination.

What does off-label usage mean?

Off-label usage refers to the practice of prescribing or using a medication, medical device, or treatment for a purpose that is not approved by regulatory authorities, such as the FDA (Food and Drug Administration) in the United States. This means that the medication is being used in a manner or for a condition that is not specifically listed on its label or approved product information. Off-label usage may occur when healthcare professionals believe that the treatment may be beneficial for a particular condition, based on clinical judgment, research, or anecdotal evidence, even if it has not been formally approved for that specific use.

Am I a good candidate?

A good candidate for Tadalafil typically includes individuals experiencing erectile dysfunction or symptoms of benign prostatic hyperplasia, after consulting with a healthcare provider to assess their medical history and overall health. Compatibility with other medications, cardiovascular health, and lifestyle factors are also important considerations in determining suitability for Tadalafil usage.

What states is this available in?

California, New York, Florida, Texas, Colorado and Nevada

Supporting science and sources

How do I use Tadalafil?

Tadalafil is typically taken orally before anticipated sexual activity, with or without food, as directed by a healthcare professional.

How does Tadalafil effect my body?

Tadalafil, upon oral administration, is rapidly absorbed in the gastrointestinal tract, with peak plasma concentrations reached within 2 hours. It undergoes hepatic metabolism primarily by the cytochrome P450 enzyme system, particularly CYP3A4. The major metabolite is further excreted in the feces and urine.

Special Considerations

Tadalafil is contraindicated in individuals with a known hypersensitivity to the drug or any of its components. It is essential to exercise caution in patients with cardiovascular conditions, as the use of Tadalafil may pose risks, particularly during sexual activity. Individuals with a history of priapism or conditions predisposing to priapism, such as sickle cell anemia, should use Tadalafil cautiously. Before using Tadalafil, consultation with healthcare professionals is recommended, especially for individuals with severe hepatic or renal impairment. As with any medication, it is crucial to follow prescribed dosages and seek immediate medical attention in case of adverse reactions.

How do I safely store Tadalafil?

Tadalafil should be stored at room temperature away from moisture, heat, and light. Keeping the medication in its original packaging and away from children and pets is essential to maintain its stability and effectiveness.

What’s the difference between Tadalafil and Cialis?

Tadalafil is the active ingredient used in Cialis and is the generic equivalent. As clinically evidenced, Tadalafil is just as safe and effective as branded Cialis; it works for the same amount of time and delivers the same lasting effects.

What are the advantages of Tadalafil over other ED meds?

Unlike other ED medications, Tadalafil can be taken daily. This means you can be intimate at any time, rather than needing to take a pill from time to time, as needed, like other brands.



Clinical evidence also supports Tadalafil for a variety of health and longevity benefits due to its ability to act as an anti-inflammatory, improve cognitive function, and improve blood flow to major organs.

Can Tadalafil be used for purposes other than erectile dysfunction?

Yes, besides treating erectile dysfunction, Tadalafil is also prescribed for managing symptoms of benign prostatic hyperplasia (BPH), a condition characterized by an enlarged prostate gland. By relaxing the muscles in the prostate and bladder, Tadalafil can help improve urinary symptoms associated with BPH, such as difficulty urinating or frequent urination.

What does off-label usage mean?

Off-label usage refers to the practice of prescribing or using a medication, medical device, or treatment for a purpose that is not approved by regulatory authorities, such as the FDA (Food and Drug Administration) in the United States. This means that the medication is being used in a manner or for a condition that is not specifically listed on its label or approved product information. Off-label usage may occur when healthcare professionals believe that the treatment may be beneficial for a particular condition, based on clinical judgment, research, or anecdotal evidence, even if it has not been formally approved for that specific use.

Am I a good candidate?

A good candidate for Tadalafil typically includes individuals experiencing erectile dysfunction or symptoms of benign prostatic hyperplasia, after consulting with a healthcare provider to assess their medical history and overall health. Compatibility with other medications, cardiovascular health, and lifestyle factors are also important considerations in determining suitability for Tadalafil usage.

What states is this available in?

California, New York, Florida, Texas, Colorado and Nevada

Supporting science and sources

How do I use Tadalafil?

Tadalafil is typically taken orally before anticipated sexual activity, with or without food, as directed by a healthcare professional.

How does Tadalafil effect my body?

Tadalafil, upon oral administration, is rapidly absorbed in the gastrointestinal tract, with peak plasma concentrations reached within 2 hours. It undergoes hepatic metabolism primarily by the cytochrome P450 enzyme system, particularly CYP3A4. The major metabolite is further excreted in the feces and urine.

Special Considerations

Tadalafil is contraindicated in individuals with a known hypersensitivity to the drug or any of its components. It is essential to exercise caution in patients with cardiovascular conditions, as the use of Tadalafil may pose risks, particularly during sexual activity. Individuals with a history of priapism or conditions predisposing to priapism, such as sickle cell anemia, should use Tadalafil cautiously. Before using Tadalafil, consultation with healthcare professionals is recommended, especially for individuals with severe hepatic or renal impairment. As with any medication, it is crucial to follow prescribed dosages and seek immediate medical attention in case of adverse reactions.

How do I safely store Tadalafil?

Tadalafil should be stored at room temperature away from moisture, heat, and light. Keeping the medication in its original packaging and away from children and pets is essential to maintain its stability and effectiveness.

What’s the difference between Tadalafil and Cialis?

Tadalafil is the active ingredient used in Cialis and is the generic equivalent. As clinically evidenced, Tadalafil is just as safe and effective as branded Cialis; it works for the same amount of time and delivers the same lasting effects.

What are the advantages of Tadalafil over other ED meds?

Unlike other ED medications, Tadalafil can be taken daily. This means you can be intimate at any time, rather than needing to take a pill from time to time, as needed, like other brands.



Clinical evidence also supports Tadalafil for a variety of health and longevity benefits due to its ability to act as an anti-inflammatory, improve cognitive function, and improve blood flow to major organs.

Can Tadalafil be used for purposes other than erectile dysfunction?

Yes, besides treating erectile dysfunction, Tadalafil is also prescribed for managing symptoms of benign prostatic hyperplasia (BPH), a condition characterized by an enlarged prostate gland. By relaxing the muscles in the prostate and bladder, Tadalafil can help improve urinary symptoms associated with BPH, such as difficulty urinating or frequent urination.

What does off-label usage mean?

Off-label usage refers to the practice of prescribing or using a medication, medical device, or treatment for a purpose that is not approved by regulatory authorities, such as the FDA (Food and Drug Administration) in the United States. This means that the medication is being used in a manner or for a condition that is not specifically listed on its label or approved product information. Off-label usage may occur when healthcare professionals believe that the treatment may be beneficial for a particular condition, based on clinical judgment, research, or anecdotal evidence, even if it has not been formally approved for that specific use.

Am I a good candidate?

A good candidate for Tadalafil typically includes individuals experiencing erectile dysfunction or symptoms of benign prostatic hyperplasia, after consulting with a healthcare provider to assess their medical history and overall health. Compatibility with other medications, cardiovascular health, and lifestyle factors are also important considerations in determining suitability for Tadalafil usage.

What states is this available in?

California, New York, Florida, Texas, Colorado and Nevada

Supporting science and sources

How do I use Tadalafil?

Tadalafil is typically taken orally before anticipated sexual activity, with or without food, as directed by a healthcare professional.

How does Tadalafil effect my body?

Tadalafil, upon oral administration, is rapidly absorbed in the gastrointestinal tract, with peak plasma concentrations reached within 2 hours. It undergoes hepatic metabolism primarily by the cytochrome P450 enzyme system, particularly CYP3A4. The major metabolite is further excreted in the feces and urine.

Special Considerations

Tadalafil is contraindicated in individuals with a known hypersensitivity to the drug or any of its components. It is essential to exercise caution in patients with cardiovascular conditions, as the use of Tadalafil may pose risks, particularly during sexual activity. Individuals with a history of priapism or conditions predisposing to priapism, such as sickle cell anemia, should use Tadalafil cautiously. Before using Tadalafil, consultation with healthcare professionals is recommended, especially for individuals with severe hepatic or renal impairment. As with any medication, it is crucial to follow prescribed dosages and seek immediate medical attention in case of adverse reactions.

How do I safely store Tadalafil?

Tadalafil should be stored at room temperature away from moisture, heat, and light. Keeping the medication in its original packaging and away from children and pets is essential to maintain its stability and effectiveness.

What’s the difference between Tadalafil and Cialis?

Tadalafil is the active ingredient used in Cialis and is the generic equivalent. As clinically evidenced, Tadalafil is just as safe and effective as branded Cialis; it works for the same amount of time and delivers the same lasting effects.

What are the advantages of Tadalafil over other ED meds?

Unlike other ED medications, Tadalafil can be taken daily. This means you can be intimate at any time, rather than needing to take a pill from time to time, as needed, like other brands.



Clinical evidence also supports Tadalafil for a variety of health and longevity benefits due to its ability to act as an anti-inflammatory, improve cognitive function, and improve blood flow to major organs.

Can Tadalafil be used for purposes other than erectile dysfunction?

Yes, besides treating erectile dysfunction, Tadalafil is also prescribed for managing symptoms of benign prostatic hyperplasia (BPH), a condition characterized by an enlarged prostate gland. By relaxing the muscles in the prostate and bladder, Tadalafil can help improve urinary symptoms associated with BPH, such as difficulty urinating or frequent urination.

What does off-label usage mean?

Off-label usage refers to the practice of prescribing or using a medication, medical device, or treatment for a purpose that is not approved by regulatory authorities, such as the FDA (Food and Drug Administration) in the United States. This means that the medication is being used in a manner or for a condition that is not specifically listed on its label or approved product information. Off-label usage may occur when healthcare professionals believe that the treatment may be beneficial for a particular condition, based on clinical judgment, research, or anecdotal evidence, even if it has not been formally approved for that specific use.

Am I a good candidate?

A good candidate for Tadalafil typically includes individuals experiencing erectile dysfunction or symptoms of benign prostatic hyperplasia, after consulting with a healthcare provider to assess their medical history and overall health. Compatibility with other medications, cardiovascular health, and lifestyle factors are also important considerations in determining suitability for Tadalafil usage.

What states is this available in?

California, New York, Florida, Texas, Colorado and Nevada

Supporting science and sources

How do I use Tadalafil?

Tadalafil is typically taken orally before anticipated sexual activity, with or without food, as directed by a healthcare professional.

How does Tadalafil effect my body?

Tadalafil, upon oral administration, is rapidly absorbed in the gastrointestinal tract, with peak plasma concentrations reached within 2 hours. It undergoes hepatic metabolism primarily by the cytochrome P450 enzyme system, particularly CYP3A4. The major metabolite is further excreted in the feces and urine.

Special Considerations

Tadalafil is contraindicated in individuals with a known hypersensitivity to the drug or any of its components. It is essential to exercise caution in patients with cardiovascular conditions, as the use of Tadalafil may pose risks, particularly during sexual activity. Individuals with a history of priapism or conditions predisposing to priapism, such as sickle cell anemia, should use Tadalafil cautiously. Before using Tadalafil, consultation with healthcare professionals is recommended, especially for individuals with severe hepatic or renal impairment. As with any medication, it is crucial to follow prescribed dosages and seek immediate medical attention in case of adverse reactions.

How do I safely store Tadalafil?

Tadalafil should be stored at room temperature away from moisture, heat, and light. Keeping the medication in its original packaging and away from children and pets is essential to maintain its stability and effectiveness.

What’s the difference between Tadalafil and Cialis?

Tadalafil is the active ingredient used in Cialis and is the generic equivalent. As clinically evidenced, Tadalafil is just as safe and effective as branded Cialis; it works for the same amount of time and delivers the same lasting effects.

What are the advantages of Tadalafil over other ED meds?

Unlike other ED medications, Tadalafil can be taken daily. This means you can be intimate at any time, rather than needing to take a pill from time to time, as needed, like other brands.



Clinical evidence also supports Tadalafil for a variety of health and longevity benefits due to its ability to act as an anti-inflammatory, improve cognitive function, and improve blood flow to major organs.

Can Tadalafil be used for purposes other than erectile dysfunction?

Yes, besides treating erectile dysfunction, Tadalafil is also prescribed for managing symptoms of benign prostatic hyperplasia (BPH), a condition characterized by an enlarged prostate gland. By relaxing the muscles in the prostate and bladder, Tadalafil can help improve urinary symptoms associated with BPH, such as difficulty urinating or frequent urination.

What does off-label usage mean?

Off-label usage refers to the practice of prescribing or using a medication, medical device, or treatment for a purpose that is not approved by regulatory authorities, such as the FDA (Food and Drug Administration) in the United States. This means that the medication is being used in a manner or for a condition that is not specifically listed on its label or approved product information. Off-label usage may occur when healthcare professionals believe that the treatment may be beneficial for a particular condition, based on clinical judgment, research, or anecdotal evidence, even if it has not been formally approved for that specific use.

Am I a good candidate?

A good candidate for Tadalafil typically includes individuals experiencing erectile dysfunction or symptoms of benign prostatic hyperplasia, after consulting with a healthcare provider to assess their medical history and overall health. Compatibility with other medications, cardiovascular health, and lifestyle factors are also important considerations in determining suitability for Tadalafil usage.

What states is this available in?

California, New York, Florida, Texas, Colorado and Nevada

Supporting science and sources

How do I use Tadalafil?

Tadalafil is typically taken orally before anticipated sexual activity, with or without food, as directed by a healthcare professional.

How does Tadalafil effect my body?

Tadalafil, upon oral administration, is rapidly absorbed in the gastrointestinal tract, with peak plasma concentrations reached within 2 hours. It undergoes hepatic metabolism primarily by the cytochrome P450 enzyme system, particularly CYP3A4. The major metabolite is further excreted in the feces and urine.

Special Considerations

Tadalafil is contraindicated in individuals with a known hypersensitivity to the drug or any of its components. It is essential to exercise caution in patients with cardiovascular conditions, as the use of Tadalafil may pose risks, particularly during sexual activity. Individuals with a history of priapism or conditions predisposing to priapism, such as sickle cell anemia, should use Tadalafil cautiously. Before using Tadalafil, consultation with healthcare professionals is recommended, especially for individuals with severe hepatic or renal impairment. As with any medication, it is crucial to follow prescribed dosages and seek immediate medical attention in case of adverse reactions.

How do I safely store Tadalafil?

Tadalafil should be stored at room temperature away from moisture, heat, and light. Keeping the medication in its original packaging and away from children and pets is essential to maintain its stability and effectiveness.

What’s the difference between Tadalafil and Cialis?

Tadalafil is the active ingredient used in Cialis and is the generic equivalent. As clinically evidenced, Tadalafil is just as safe and effective as branded Cialis; it works for the same amount of time and delivers the same lasting effects.

What are the advantages of Tadalafil over other ED meds?

Unlike other ED medications, Tadalafil can be taken daily. This means you can be intimate at any time, rather than needing to take a pill from time to time, as needed, like other brands.



Clinical evidence also supports Tadalafil for a variety of health and longevity benefits due to its ability to act as an anti-inflammatory, improve cognitive function, and improve blood flow to major organs.

Can Tadalafil be used for purposes other than erectile dysfunction?

Yes, besides treating erectile dysfunction, Tadalafil is also prescribed for managing symptoms of benign prostatic hyperplasia (BPH), a condition characterized by an enlarged prostate gland. By relaxing the muscles in the prostate and bladder, Tadalafil can help improve urinary symptoms associated with BPH, such as difficulty urinating or frequent urination.

What does off-label usage mean?

Off-label usage refers to the practice of prescribing or using a medication, medical device, or treatment for a purpose that is not approved by regulatory authorities, such as the FDA (Food and Drug Administration) in the United States. This means that the medication is being used in a manner or for a condition that is not specifically listed on its label or approved product information. Off-label usage may occur when healthcare professionals believe that the treatment may be beneficial for a particular condition, based on clinical judgment, research, or anecdotal evidence, even if it has not been formally approved for that specific use.

Am I a good candidate?

A good candidate for Tadalafil typically includes individuals experiencing erectile dysfunction or symptoms of benign prostatic hyperplasia, after consulting with a healthcare provider to assess their medical history and overall health. Compatibility with other medications, cardiovascular health, and lifestyle factors are also important considerations in determining suitability for Tadalafil usage.

What states is this available in?

California, New York, Florida, Texas, Colorado and Nevada

Supporting science and sources

How do I use Tadalafil?

Tadalafil is typically taken orally before anticipated sexual activity, with or without food, as directed by a healthcare professional.

How does Tadalafil effect my body?

Tadalafil, upon oral administration, is rapidly absorbed in the gastrointestinal tract, with peak plasma concentrations reached within 2 hours. It undergoes hepatic metabolism primarily by the cytochrome P450 enzyme system, particularly CYP3A4. The major metabolite is further excreted in the feces and urine.

Special Considerations

Tadalafil is contraindicated in individuals with a known hypersensitivity to the drug or any of its components. It is essential to exercise caution in patients with cardiovascular conditions, as the use of Tadalafil may pose risks, particularly during sexual activity. Individuals with a history of priapism or conditions predisposing to priapism, such as sickle cell anemia, should use Tadalafil cautiously. Before using Tadalafil, consultation with healthcare professionals is recommended, especially for individuals with severe hepatic or renal impairment. As with any medication, it is crucial to follow prescribed dosages and seek immediate medical attention in case of adverse reactions.

How do I safely store Tadalafil?

Tadalafil should be stored at room temperature away from moisture, heat, and light. Keeping the medication in its original packaging and away from children and pets is essential to maintain its stability and effectiveness.

What’s the difference between Tadalafil and Cialis?

Tadalafil is the active ingredient used in Cialis and is the generic equivalent. As clinically evidenced, Tadalafil is just as safe and effective as branded Cialis; it works for the same amount of time and delivers the same lasting effects.

What are the advantages of Tadalafil over other ED meds?

Unlike other ED medications, Tadalafil can be taken daily. This means you can be intimate at any time, rather than needing to take a pill from time to time, as needed, like other brands.



Clinical evidence also supports Tadalafil for a variety of health and longevity benefits due to its ability to act as an anti-inflammatory, improve cognitive function, and improve blood flow to major organs.

Can Tadalafil be used for purposes other than erectile dysfunction?

Yes, besides treating erectile dysfunction, Tadalafil is also prescribed for managing symptoms of benign prostatic hyperplasia (BPH), a condition characterized by an enlarged prostate gland. By relaxing the muscles in the prostate and bladder, Tadalafil can help improve urinary symptoms associated with BPH, such as difficulty urinating or frequent urination.

What does off-label usage mean?

Off-label usage refers to the practice of prescribing or using a medication, medical device, or treatment for a purpose that is not approved by regulatory authorities, such as the FDA (Food and Drug Administration) in the United States. This means that the medication is being used in a manner or for a condition that is not specifically listed on its label or approved product information. Off-label usage may occur when healthcare professionals believe that the treatment may be beneficial for a particular condition, based on clinical judgment, research, or anecdotal evidence, even if it has not been formally approved for that specific use.

Am I a good candidate?

A good candidate for Tadalafil typically includes individuals experiencing erectile dysfunction or symptoms of benign prostatic hyperplasia, after consulting with a healthcare provider to assess their medical history and overall health. Compatibility with other medications, cardiovascular health, and lifestyle factors are also important considerations in determining suitability for Tadalafil usage.

What states is this available in?

California, New York, Florida, Texas, Colorado and Nevada

Supporting science and sources

How do I use Tadalafil?

Tadalafil is typically taken orally before anticipated sexual activity, with or without food, as directed by a healthcare professional.

How does Tadalafil effect my body?

Tadalafil, upon oral administration, is rapidly absorbed in the gastrointestinal tract, with peak plasma concentrations reached within 2 hours. It undergoes hepatic metabolism primarily by the cytochrome P450 enzyme system, particularly CYP3A4. The major metabolite is further excreted in the feces and urine.

Special Considerations

Tadalafil is contraindicated in individuals with a known hypersensitivity to the drug or any of its components. It is essential to exercise caution in patients with cardiovascular conditions, as the use of Tadalafil may pose risks, particularly during sexual activity. Individuals with a history of priapism or conditions predisposing to priapism, such as sickle cell anemia, should use Tadalafil cautiously. Before using Tadalafil, consultation with healthcare professionals is recommended, especially for individuals with severe hepatic or renal impairment. As with any medication, it is crucial to follow prescribed dosages and seek immediate medical attention in case of adverse reactions.

How do I safely store Tadalafil?

Tadalafil should be stored at room temperature away from moisture, heat, and light. Keeping the medication in its original packaging and away from children and pets is essential to maintain its stability and effectiveness.

What’s the difference between Tadalafil and Cialis?

Tadalafil is the active ingredient used in Cialis and is the generic equivalent. As clinically evidenced, Tadalafil is just as safe and effective as branded Cialis; it works for the same amount of time and delivers the same lasting effects.

What are the advantages of Tadalafil over other ED meds?

Unlike other ED medications, Tadalafil can be taken daily. This means you can be intimate at any time, rather than needing to take a pill from time to time, as needed, like other brands.



Clinical evidence also supports Tadalafil for a variety of health and longevity benefits due to its ability to act as an anti-inflammatory, improve cognitive function, and improve blood flow to major organs.

Can Tadalafil be used for purposes other than erectile dysfunction?

Yes, besides treating erectile dysfunction, Tadalafil is also prescribed for managing symptoms of benign prostatic hyperplasia (BPH), a condition characterized by an enlarged prostate gland. By relaxing the muscles in the prostate and bladder, Tadalafil can help improve urinary symptoms associated with BPH, such as difficulty urinating or frequent urination.

What does off-label usage mean?

Off-label usage refers to the practice of prescribing or using a medication, medical device, or treatment for a purpose that is not approved by regulatory authorities, such as the FDA (Food and Drug Administration) in the United States. This means that the medication is being used in a manner or for a condition that is not specifically listed on its label or approved product information. Off-label usage may occur when healthcare professionals believe that the treatment may be beneficial for a particular condition, based on clinical judgment, research, or anecdotal evidence, even if it has not been formally approved for that specific use.

For Superpower Members, text your private concierge at any time with any question

Important safety information

Potential Side Effects

Common side effects of Tadalafil may include headache, flushing, dyspepsia, back pain, myalgia, and nasal congestion. If these symptoms persist or worsen, individuals should seek medical advice promptly.

Contraindications
  • Allergies or Hypersensitivity: Avoid Tadalafil if you have known allergies or hypersensitivity to the drug or any of its components.
  • Cardiovascular Conditions: Exercise caution in individuals with cardiovascular conditions, as the use of Tadalafil may pose a risk, particularly during sexual activity.
  • Priapism History: Use Tadalafil cautiously in patients with a history of priapism or conditions predisposing to priapism, such as sickle cell anemia.
  • Hepatic or Renal Impairment: Consult healthcare professionals before using Tadalafil if you have severe hepatic or renal impairment.

Drug Interactions

Tadalafil may interact with medications containing nitrates, alpha-blockers, antihypertensives, or other drugs, leading to potentially dangerous hypotensive effects. Patients should inform healthcare providers of all medications, including over-the-counter and herbal supplements, to assess potential interactions.

Potential Side Effects

Common side effects of Tadalafil may include headache, flushing, dyspepsia, back pain, myalgia, and nasal congestion. If these symptoms persist or worsen, individuals should seek medical advice promptly.

Contraindications
  • Allergies or Hypersensitivity: Avoid Tadalafil if you have known allergies or hypersensitivity to the drug or any of its components.
  • Cardiovascular Conditions: Exercise caution in individuals with cardiovascular conditions, as the use of Tadalafil may pose a risk, particularly during sexual activity.
  • Priapism History: Use Tadalafil cautiously in patients with a history of priapism or conditions predisposing to priapism, such as sickle cell anemia.
  • Hepatic or Renal Impairment: Consult healthcare professionals before using Tadalafil if you have severe hepatic or renal impairment.

Drug Interactions

Tadalafil may interact with medications containing nitrates, alpha-blockers, antihypertensives, or other drugs, leading to potentially dangerous hypotensive effects. Patients should inform healthcare providers of all medications, including over-the-counter and herbal supplements, to assess potential interactions.

Potential Side Effects

Common side effects of Tadalafil may include headache, flushing, dyspepsia, back pain, myalgia, and nasal congestion. If these symptoms persist or worsen, individuals should seek medical advice promptly.

Contraindications
  • Allergies or Hypersensitivity: Avoid Tadalafil if you have known allergies or hypersensitivity to the drug or any of its components.
  • Cardiovascular Conditions: Exercise caution in individuals with cardiovascular conditions, as the use of Tadalafil may pose a risk, particularly during sexual activity.
  • Priapism History: Use Tadalafil cautiously in patients with a history of priapism or conditions predisposing to priapism, such as sickle cell anemia.
  • Hepatic or Renal Impairment: Consult healthcare professionals before using Tadalafil if you have severe hepatic or renal impairment.

Drug Interactions

Tadalafil may interact with medications containing nitrates, alpha-blockers, antihypertensives, or other drugs, leading to potentially dangerous hypotensive effects. Patients should inform healthcare providers of all medications, including over-the-counter and herbal supplements, to assess potential interactions.

For Superpower Members, text your private concierge at any time with any question

Our Curation Standards

At Superpower, we believe in scientific rigor and transparency. We have a dedicated medical and research team that follows a multi-faceted curation and evaluation process to select only the most trusted and efficacious products and protocols for our members.

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